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Spicy Southern Cheesy Chicken Spaghetti Casserole

A creamy, comforting casserole filled with chicken, pasta, and gooey cheese, perfect for weeknight meals.
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Prep Time 20 minutes
Cook Time 35 minutes
Total Time 55 minutes
Servings: 6 servings
Course: Dinner, Main Course
Cuisine: American, Southern
Calories: 450
Ingredients Method Notes

Ingredients
  

Main Ingredients
  • 1.5 lbs boneless, skinless chicken breasts About 3-4 breasts
  • 8 oz spaghetti Cooked until al dente
  • 2 cups shredded sharp cheddar cheese Divided, half for mixing, half for topping
  • 1 cup fresh bell peppers (chopped) Add color and flavor
  • 10.5 oz cream of chicken soup For creaminess in the casserole
  • 1 tsp paprika For flavor
  • 1/2 tsp cayenne pepper Adjust to taste
  • 1 tsp garlic powder For added flavor
  • 1/4 cup green onions (sliced) For garnish

Method
 

Preparation
  1. Preheat your oven to 350°F (175°C) and grease a large casserole dish.
  2. Cook the chicken in a large pot over medium heat for about 6-7 minutes per side until golden and cooked through.
  3. In a separate pot, boil salted water and cook spaghetti until al dente (8-10 minutes). Drain and set aside.
Mixing
  1. In a bowl, mix the shredded chicken, cooked spaghetti, cream of chicken soup, bell peppers, paprika, cayenne pepper, garlic powder, and half of the cheddar cheese until well combined.
Baking
  1. Transfer the mixture to the greased casserole dish and top with the remaining cheddar cheese.
  2. Bake for 25-30 minutes until bubbly and golden brown.
  3. Let it rest for 5 minutes before garnishing with chopped green onions and serving.

Notes

For serving, pair with a fresh salad or garlic bread. Store leftovers in the fridge for about 3-4 days or freeze for 2-3 months. Reheat gently to maintain texture.