Mac and Cheese Meatloaf Casserole: The Ultimate Comfort Food Mashup
Ever had a meatloaf that made you want to hug your plate?
This Mac and Cheese Meatloaf Casserole is an absolute game changer! Imagine the creamy goodness of mac and cheese combined with the hearty flavors of classic meatloaf—this dish is definitely a match made in comfort food heaven. Not only is it a one-pan wonder, but it’s also perfect for busy weeknights and gatherings alike. Let’s dive into why this cozy dish is destined for your dinner table!
Why Make This Recipe
Who doesn’t want an easy cleanup after a delicious dinner? This casserole requires minimal dishes and packs a punch of flavors that everyone in the family will adore. Plus, it’s super affordable given the simple ingredients. You’ll impress your loved ones without breaking the bank! Seriously, this is comfort food that your entire crew will thrive on—talk about a win-win! 😄
Ingredients
You don’t need fancy stuff — just these basics!
- 1 lb ground beef
- 2 cups uncooked macaroni
- 2 cups shredded cheddar cheese
- 1/2 cup diced onion
- 1/2 cup breadcrumbs
- 1 large egg
- 1/4 cup milk (for meatloaf)
- 2 tbsp butter (for cheese sauce)
- 2 cups milk (for cheese sauce)
- 1 tsp salt
- 1/2 tsp pepper
- 1/2 tsp paprika
- 1/2 tsp dry mustard
- 2 tbsp flour
Directions
Making this casserole is as easy as 1-2-3!
- Preheat your oven to 350°F (175°C).
- In a mixing bowl, combine ground beef, onion, breadcrumbs, egg, milk, salt, and pepper. Mix well and press into a greased baking dish.
- Bake the meatloaf for 20 minutes.
- While it bakes, cook macaroni according to package directions; drain and set aside.
- For the cheese sauce, melt butter in a saucepan over medium heat. Stir in flour and cook for one minute.
- Gradually whisk in milk until thickened; season with salt, pepper, paprika, and dry mustard. Stir in shredded cheese until melted.
- Combine cooked macaroni with the cheese sauce and pour over the meatloaf layer. Top with remaining cheese.
- Bake for an additional 25 minutes or until bubbly.

How to Make Mac and Cheese Meatloaf Casserole: The Ultimate Comfort Food Mashup (Overview)
Picture this: You mix together all the meatloaf goodies in a bowl and bake while your macaroni is cooking, so you’re not left staring at a pot of boiling water. Pro tip? Don’t skip browning the meatloaf—it adds a lovely depth of flavor! Once that melt-in-your-mouth cheese sauce comes together and mingles with those perfectly cooked macaroni noodles, you’ll know you’re in for a treat!
How to Serve Mac and Cheese Meatloaf Casserole: The Ultimate Comfort Food Mashup
When it comes to serving, you can’t go wrong! This dish is a beautiful union of colors—golden cheese on top, rich meatloaf underneath, and creamy pasta nestled in between. Pair it with a fresh side salad for a nice crunch and aroma. A sprinkling of fresh herbs like parsley can elevate your presentation game, too. Who doesn’t love a dish that looks as good as it tastes? 😍
How to Store Mac and Cheese Meatloaf Casserole: The Ultimate Comfort Food Mashup
Got leftovers? Lucky you! This casserole keeps well in the refrigerator for up to 3 days. You can also freeze it for up to 3 months—just make sure to wrap it tightly! Reheat in the oven or microwave, and you’ll have that creamy goodness back in no time. This is a perfect make-ahead meal for those busy weeks!
Tips to Make Mac and Cheese Meatloaf Casserole: The Ultimate Comfort Food Mashup
- Use lean ground beef for a healthier option or swap it out for turkey!
- Experiment with cheeses—mix in Monterey Jack for extra creaminess.
- Want crispy edges? Broil the casserole for the last couple of minutes!
- Add in veggies like spinach or bell peppers for a nutritional boost.
- Taste your cheese sauce before adding it to the casserole; adjust seasoning to suit your palate!
Variation
Feeling like a twist on tradition? Try adding a scoop of BBQ sauce into the meat mixture or swap out pasta for gluten-free options. Plus, you can make this vegan by using plant-based ground meat, vegan cheese, and a flax egg. The possibilities are endless!
FAQs
1. Can I make this casserole ahead of time?
Yes! Assemble the casserole, cover it, and refrigerate. Just pop it in the oven when ready to bake.
2. How can I prevent the macaroni from being mushy?
Cook the pasta al dente, as it will continue to cook while baking in the casserole.
3. Can I freeze leftovers?
Absolutely! Freeze in an airtight container for quick meals later. Just thaw and reheat.
📌 Pin this recipe for your next cozy dinner night!

Mac and Cheese Meatloaf Casserole
Ingredients
Method
- Preheat your oven to 350°F (175°C).
- In a mixing bowl, combine ground beef, onion, breadcrumbs, egg, milk, salt, and pepper. Mix well and press into a greased baking dish.
- Bake the meatloaf for 20 minutes.
- While it bakes, cook macaroni according to package directions; drain and set aside.
- For the cheese sauce, melt butter in a saucepan over medium heat. Stir in flour and cook for one minute.
- Gradually whisk in milk until thickened; season with salt, pepper, paprika, and dry mustard. Stir in shredded cheese until melted.
- Combine cooked macaroni with the cheese sauce and pour over the meatloaf layer.
- Top with remaining cheese.
- Bake for an additional 25 minutes or until bubbly.






